The first screening in pregnancy
Pregnancy And Childbirth / / August 12, 2017
First Screening during pregnancy
first screening in pregnancy is an important examination, the results of which are important for estimating the probability of the presence of the fetus of different chromosomal abnormalities.
When a woman has become pregnant screening of the first trimester and the second it necessarily offers the attending gynecologist.Since even those parents who, regardless of the features of the child's health, never accept abortion, should be ready for the birth of a child with abnormalities, if the results of invasive diagnosis is confirmed.
first screening in pregnancy is the timing of - the end of the 1st and the beginning of the 2nd trimester.Namely, at 12-13 weeks of a woman doing ultrasound, where the doctor is required to measure the TVP (nuchal translucency).As well as donating blood from a vein in 2 indicators: hCG and PAPP-A.The first biochemical screening in pregnancy rate at 12-13 weeks of PAPP-A - 1,03 - 6,01.For a period of 13-14 weeks, this figure should be equalto 1.47 - 8.54.HCG at 11-12 weeks should be equal to 20000-90000, at 13-14 weeks - 15000-16000.
second screening during pregnancy is carried out from 16 to 20 per week.Namely, donates blood at time of 16-18 weeks AFP, hCG and estriol-A.A ultrasound is performed at 20-22 weeks.HCG rate for 17-24 weeks 4,060 - 165.400 mIU / mL (mIU / ml).Norma AFP in 15-19 weeks, 15-95 U / ml, 0.5 to 2 MoM.Estriol-A normally 0.5-2 MoM.If any of these indicators are not normal, this may indicate a wrong definition of the duration of pregnancy or the risk of a chromosomal aberrations in the fetus.
But first ultrasound screening in pregnancy, nor the second, or rather individual test results can not be considered as an indication for invasive diagnostics.Geneticist should make a quantitative assessment of the individual risk of various pathologies.Calculation of the conducting special program.When it takes into account the woman's age, number of fruits, a variety of diseases, etc. In other words, the result should be presented like this:.
- risk of Down's syndrome: 1: 1400
- risk of Patau syndrome: 1: 1900
This means that whensuch as the results of the survey 1 in 1400 pregnant women, a child is born with Down syndrome and a 1 in 1900 with Patau syndrome.
If screening during pregnancy indicates a high risk of any pathology, paired recommend invasive diagnostics.For a period of 11-14 weeks is horionbiopsiya in 16-20 weeks amniocentesis after 20 weeks cordocentesis.These studies help to give almost 100% correct answer on genetic "health" of the fetus.The disadvantage here is that 1-2% of women as a result of the procedures can happen miscarriage.The safest considered amniocentesis.Each pair decides - whether to carry out invasive diagnostics.If the result of its determination is chromosomal abnormality - a woman offering abortion.